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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270bb8367082466376911734e3e57dbbfa825fd9b3dce1d70b5b35fa5686587a' 
  AND token = '5bs/RknUXQCnyyJLU5KbnnxGcfzFuf1EJgnibgl+Ga4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}