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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b8aa94e0baf8df97fd8fac3b9557e4e3726c3e6d71abcd921c6ce4e49fe57f' 
  AND token = 'pWHwGIdTEDCPifswKc+U+8QCwkrcIDaXVHBokPYldw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}