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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc246e8a3e40a3489e033fd4e100de32482e5fdcc93d8f5c7049cfc32c6b01a' 
  AND token = 'e4xNjcK9hQDAUotfaBXPrIz1v33bg+i3PwNths38bpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}