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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0001581752b7dea9cfe711950500dc5a2d5f9bcca0cd6163f4ccb17f106e55' 
  AND token = '5gud+gHfIrP5OvHLnV9sngB8INlFfe/PDqGXdu6dzSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}