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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4950c96c6363ddc954af664d3abdae6b4cf9a986ac448bb6fa9d55932777733' 
  AND token = '5qGUqe1d96sa7cucwdz9NfPlp2XYOid0i9zvD7wFd3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}