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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe2debef7aaf04cd31a443a5b8ce13962bdfff031e1157864349e87750595ed' 
  AND token = 'O+yuvN81TvH0F2DzJI8rqhnOMplsl6lnx5A2pz3iP7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}