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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e662c6e6e30917592af26cd44517c0934d462932f6abeed0de5360e115f7ae8' 
  AND token = '3ioll5ok+Sglqo9CH5FGx9QuYjH+HAB+vJyCvZCBoOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}