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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42133a9261adea5349c13c22a67a0e3f7796a2d0545e87bcf9393984b011d9d' 
  AND token = 'swRGeHGblEjGL7aNMAOuy+uTKB8jktxZCapYnfHarWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}