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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3424256947791881773d4e6e12357e98e738c2ea9e8a5a0089574e9be1645a5e' 
  AND token = 'lYZiS5tkptCy45yaD0Mm9ib0+92jiQEM5mJUlGnW2OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}