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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de51c449c75fdb4ce74d226cde43b2c1c6a0a19fc27564fb96ca53f1f41220d' 
  AND token = 'ONVdv2E4TkfrLoaJU155wtSrb9HR8Dcz1scT7FtJKs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}