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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e7122b3000b759362ce2b19621085e26d52fbcee82b8782d321c0ab749ca48' 
  AND token = 'KLPh7iInpDTN+7aQPNqDegCxj/+tbEXYP1HWwMYdpEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}