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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de13d8ff417f299c313c7a65e936450a75916857da3cc0e30ea4b149baf85085' 
  AND token = 'Z5Iz7yIAs+py/HivHiHR3Zz/AoDO0LgnMCftXx3LVr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}