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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aededa12c16a94569d006a3d45f5f7866a48cba26f0ae7ae09f46ff37deab025' 
  AND token = 'Dw5cr5ukUHMyAw9lQBPOuLKmix/F5imXLezHdTR4jDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}