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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18bb409d79244d7d1eeda0f5f8c5eb818e2e6564b28b16516adb0e0ca395876' 
  AND token = 'fpYKcEte4gWtJ9da+nFEiuddTx3xViGLhzMPNCff5xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}