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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ab5b6b41bdee241defc5d3038b094feef279484152ad3c0535a1435d33bb2c' 
  AND token = 'lzVS6ACEcWo/A55wPJlv8iAO6SbpN2N3mh7NuawV2+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}