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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5717fe9001c53bcd37f9ba10e783d4c0271372c7fa586f1d899b47013450d7' 
  AND token = 't5FuhfcLUDo0csMOs8ZFCs1jgMhwv9SMqOSaFQUeeA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}