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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1322403452f5b423159821cbc75833144f0bee470b0d3554e765058acb5fbd9' 
  AND token = 'HXbDQzc0Py9UWMPl94N9460eTsduojnhXS7FothxtgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}