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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887783b6c7fedea839cb52a9bb5257c6293d514aeaff5fe4ddd65edbdd6f07c9' 
  AND token = 'Gtq6adh8/mARWhEfbDmx/K9AqBZbtkX9+tuwnJyT+CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}