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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fc62b2eeda32dfddb637f9d3e947bbc2ba05f049960cd25ecb5b6752910628' 
  AND token = 'VGn8S7wAjr3VtQ/RZ4NDZQewhOgztV/Ej90D1dT8zsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}