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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eb2e850890c137c47dd1f883f2839125e17b7cc0a31ba9f524d4428bd1d6a0' 
  AND token = 'o4bsZNL1ZDy/9A2J2Z91fifuooCJlSxDc+vWz4nibSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}