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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8007f2f108ba78f2a1e33a82d685d05a25fd08f46c6bb3acc4dd3090c1b748c1' 
  AND token = 'xXR/LZcecOTXKmDd4KLGhntU85U60tPZzK4IiF32qX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}