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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d2b598afbcb55123b8aae868643b08e9a2fcd736d8e3480aa54d4880d15caf1' 
  AND token = 'F5B+l7DHRuJ/tEKYp2+Re1ZSnTzpGRGAuFG2FKnsT7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}