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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b00f5ad9d0d12063229b6ca4c965d91693f9cc0d573f0c6a68bb9b97b918404' 
  AND token = '++amJUdkskn2wRzXyL698J0aNNtt74AjMyDQ7W73MnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}