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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7f6509a2f8c0b6352de7562b29da00cd7205f55f9e1e45f37bd86302b03db0c' 
  AND token = 'TMG0riRVqbnZiRVHVU/G/xSteY9EDdtW3Czt0GwVjc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}