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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd303b4d3fb1283ef8892be2e4c7b0aed87adc483a44b32f669ee7844a8ad3312' 
  AND token = '4EHko0INySsOoxHC8WxpV8w+fp//mlanvboCWdin3ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}