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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2b2ed639e14a3708849f999099e3feaaf27972200b53c8e2c766bfb2187f2e' 
  AND token = 'A2ux8onGN27xt0JtKV4X3Vuy65VRqobDnOZvEHj7l2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}