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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b1e1481b2d909db066d5d7fab400ef3d43e8de09a609110875c302af05c145' 
  AND token = '7O1JUtUSAFgj6lKSy/qtbxxcSTqh6O2m7WGMvsNaJpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}