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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c15cbff488ba70888edf3b02858ae6f6f2782779ba50e79deb33f56a89d1c4' 
  AND token = 'bS7kq2IlaiuFjSLcC9bxpRSVn7rCuszRt4XLzwLFvEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}