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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed503b253fa88c7920be97650ca6cc8d7fb5d34867b9573a566d889478a1226' 
  AND token = 'lxdPb3kMtn/hrys1ltpQORdtYvOkXLteY7XIGkFlXiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}