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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e98e932625b6b99685f18b255d9606d8560c6476cc3dc677b174683afe2172' 
  AND token = '24ixp2wFI50J3V1E6lRA9ac6UqdvM+LW1XdwJRTiDoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}