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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c910d9361af49e900a19f37e04d431ee9a99a31e057d45df58450144f1ab7163' 
  AND token = 'CGckD4s0wCNF/BHTYsDhNKaK+ZBHmeQKaOV1Hma003k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}