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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9411ea6f02c355e0a758e37c4fe747dedf28449ef3c07fd7eb3cef74b113895a' 
  AND token = 'I02cT04ZEQTFfTIYWuzr0BatlczX1ij7oEv/LdwdhNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}