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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01203337a8f4517c86d75b09a62003c25d26193a3973bb89eea77e45158a477b' 
  AND token = 'oAiodpB+d9ZxnE+gSewWokXHUDbtiNdI9POJvyCm/1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}