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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6151744f3c778bb28b62bf87e9f32dbbad5504a0261b8e205affe25b84c7975a' 
  AND token = 'xQNGB2OMfnMwTwfSxozbw0cc8cbBe4ulGGr1EfhqRpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}