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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '240dc6c64d9d773ec8e41103ff3c3e2fd9490768386d5c76c79a337607850341' 
  AND token = 'Ne6eeSUgBAIlSOKT/9Llu+OpEJDNIvrKmI/5/Kz35iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}