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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25dbf37f2f37f7b44933fd5f949d1d25e5de5eba902a385936eb15e224bde606' 
  AND token = 'Ox1mPNRJZLaR7GOMZi3S83Z21GNZ4gwOt/6CC7d3H1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}