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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0af7f2e700611cd2d402e66dda1fd3e7a6c2c9b61f67c0039c6e932e8a5f317' 
  AND token = 'UTbyxoxEaqpE74V5avuvYUuEuzb3Bj1lEJMLAkqtRLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}