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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7666e38d5b372abd4f01023b13333669f43079dbb7c9a6b774eda9e1f3421004' 
  AND token = 'WlevjOsLpdFPwcFV+iCLAMxO3b/63wiv33j0kgGHCjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}