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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2bc80cf9e04ad164b8c21f7be3f8bbea9310878c013d9994ea8a90a834ea84' 
  AND token = 'Df1O+LjcnQ/1MG0V2ExBnSqYyhBP+vOKe7FniAnRpSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}