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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9d372028314b1cd71f5fb0118625f5291198e5f2528c6fdede60b0d4b43a37' 
  AND token = 'ramBKrtMUblXlF6UsqGTnF127gMATv+8h9MxUHRvXoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}