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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763075889cfedb4a50fb3b989960e5f49bc74385a627321e9c2c87593b93aac3' 
  AND token = '2GwgJc8EgywZqfN0THVMSapsgY9B099DdLxb2n0QdSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}