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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e527d2c18b1311e7f5ce18e8d54b2669768810b90a696b5054ff1e9d24a0cf7a' 
  AND token = 'qczrzs/n+CkLxRMn7lb4jpFLwDxduYAfT+YCVOAlasc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}