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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49416af94be37bd2f0179e3daccc371434bcfba6afc2ebb31f2b0fadda4ba4ab' 
  AND token = 'g1OzA9hCS9En91FUuHE2GczQOXz10c+YTwQ+yXlQpjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}