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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191b3cbca7de065dfce1eea68c4b27581eb7fcd2e6e89e0e6be7283cb415e6e8' 
  AND token = 'TIZWDfU3dap79FedqA0H0cQnZ+fwQFFu9RjjY+Zpfhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}