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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f677e58c0cc8ad2bece689504a568c09f15c1dc28033139b5515231de0a6f0cc' 
  AND token = 'K1NekTh7m9FwiS2L7nP+2mI7HdWWN++1g5ZIFqLSvq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}