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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aad9315c8accea2cd6e152e07fbf3198334c5b38acb820d1c54a41f01bd1fb6' 
  AND token = 'fpNaryQg+yKbJ8Fce98hvUWFLk8K8MIjW0M5GY1FwdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}