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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8113618b726b2215e6e1e1a948f4f073c74b388aa15a23f9b3678917e5cae8f8' 
  AND token = 'IVWwuM5+6BfI3xvvE593bEHVU6MREHi9Yk9qVCv0uHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}