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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2e37e9d1b7f5b0846df3113ea0044b320b59d3b69e2f6fc13e70ff81221462' 
  AND token = 'Gpz4thoyhb1keNzQdm4HUYTxzNyFE9Mowp6g66xOM6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}