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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cbe6004421cd028d3fb083282cb19ecd588f544eab91440d7a5eedfe1a164d' 
  AND token = 'qBeTp9fV0mykMP46o9kxkeUMk2LaOoWkBUK+2E7rfTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}