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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4cc5b090cc40ad599a633d74aadee1451bd9bb666be9928438298fe256456dc' 
  AND token = 'rRd9ngL7GgoTWvRgGCN76SI8cCSzwxFdGd2YLkcqiaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}